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BRIEF-GSK says asthma drug Nucala (Mepolizumab) meets primary endpoints
March 6, 2017 / 3:27 PM / 7 months ago

BRIEF-GSK says asthma drug Nucala (Mepolizumab) meets primary endpoints

March 6 (Reuters) - GlaxoSmithKline Plc:

* Phase IIIB Musca study successfully met all its primary and secondary endpoints

* Patients treated with Nucala (Mepolizumab) achieved clinically and statistically significant improvements in quality of life and lung function versus placebo

* St. Georges respiratory questionnaire improved by 7.7 units from baseline versus. Placebo (p=0.001)

* Lung function (first secondary endpoint), as measured by pre-bronchodilator fev1, increased by 120ml (p=0.001) more than in placebo patients

* Asthma control showed a significant improvement versus. Placebo in Mepolizumab treatment group by 0.40 units (p<0.001)

* Safety profile of Mepolizumab in Musca study was consistent with product label for Nucala Source text for Eikon: Further company coverage: (Bengaluru Newsroom)

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