Study points to new way to test for diabetes risk

By Will Dunham

WASHINGTON (Reuters) - A protein made in the liver may give doctors a way to predict years in advance who is at high risk for the most common form of diabetes, a U.S. study published on Tuesday said.

Studying people in their 70s, the researchers found those with high levels of a protein known as fetuin-A were far more likely than those with low levels to develop type 2 diabetes over six years.

Fetuin-A is made by liver cells and may be involved in the metabolism of the sugar glucose as well as calcium, the researchers said. Type 2 diabetes is marked by high levels of glucose, the body's source of energy, in the blood.

Type 2 diabetes is the form closely linked to obesity and it has become more common worldwide. But not all obese people develop diabetes and scientists are eager to determine who might be at particular risk.

"It might ultimately be useful to use this (fetuin-A) for screening and identifying people at higher risk for diabetes," Dr. Joachim Ix of the University of California at San Diego and the San Diego Veterans Affairs Healthcare System, who led the study, said in a telephone interview.

A blood test for levels of the protein may be a promising way to assess type 2 diabetes risk and the need for steps to prevent development, Ix said.

TAKING ACTION EARLIER

"It might be that using medications that control glucose earlier might actually prevent diabetes in those people," Ix said.