Barcelona and Manchester United have featured in 10 previous European Cup/Champions League finals between them including the 2009 final when Barcelona beat United 2-0 in Rome.
They also met each other in the 1991 European Cup Winners Cup final which Manchester United won 2-1.
A look at their previous appearances in the elite competition:
Berne, May 31 1961: BENFICA 3 BARCELONA 2
Real Madrid ruled European soccer from the time the European Cup started in 1955, until their arch-rivals Barcelona beat them 4-3 on aggregate in a second-round tie in November 1960 to end their reign.
Barcelona, however, could not assume Real's mantle as European kings. Despite taking a 20th-minute lead against Benfica in the 1961 final through Sandor Kocsis, they ended up losing 3-2 to Benfica and had to wait more than three decades to emulate Real's success.
Seville, May 7 1986: STEAUA BUCHAREST 0, BARCELONA 0
(Steaua won 2-0 on penalties)
A quarter of a century on and this defeat still ranks as one of the greatest upsets in European soccer and one of the most galling for Barcelona fans to stomach.
Managed by Englishman Terry Venables, Barcelona had had a roller-coaster ride to the final, but had knocked out reigning champions Juventus along the way and were hot favourites to succeed in Seville.
However, Steaua goalkeeper Helmut Duckadam had the game of his life and Barcelona could not even find the net in the penalty shootout.
London, May 20 1992: BARCELONA 1 SAMPDORIA 0
Barcelona finally achieved the Holy Grail by lifting the European Cup in the last European Champions Cup final before the competition became known as the Champions League the following season.
Dutchman Ronald Koeman blasted home the only goal eight minutes from the end of extra time at Wembley Stadium as Barcelona lifted the yoke that had hung so heavily since Real Madrid won the first European Cup in 1956.
Athens, May 18 1994: AC MILAN 4 BARCELONA 0
Two years after being crowned European champions, Barcelona were humbled by Fabio Capello's AC Milan who overcame the absence of suspended defenders Franco Baresi and Alessandro Costacurta, and ran riot in Athens, leading 3-0 after 47 minutes with two goals from Daniele Massaro and one from Dejan Savicevic.
Marcel Desailly put the outcome beyond doubt with Milan's fourth after 58 minutes as Johan Cruyff's "dream team" crashed to defeat.
Paris, May 17, 2006: BARCELONA 2 ARSENAL 1
With 14 minutes to play at the Stade de France, Arsenal, who had played most of the match with 10 men after goalkeeper Jens Lehmann became the first player sent off in a European Cup final, were on their way to becoming the first side from London to win the competition thanks to a first-half header from Sol Campbell.
Barcelona though, had been outstanding throughout the competition and clicked into top gear when Henrik Larsson came on as a substitute midway through the second half, creating the goals for Samuel Eto'o and Juliano Belletti, who squeezed in the winner from an acute angle nine minutes from time.
Rome, May 27 2009: BARCELONA 2 MANCHESTER UNITED 0
Barcelona became the first Spanish club to win a treble of the Champions League and the domestic double when they got the better of holders Manchester United at the Olympic Stadium after Eto'o's 10th-minute opener.
The match was billed as a showdown between Barca's Argentine genius Lionel Messi and United's Portuguese hero Cristiano Ronaldo, and it was Messi who emerged victorious, scoring Barca's second with a rare header 20 minutes from time.
London, May 29 1968: MANCHESTER UNITED 4 BENFICA 1
One of European soccer's most famous matches ended in an emphatic 4-1 extra-time victory for United who were crowned kings of Europe just 10 years after the Munich air disaster all but wiped out the Busby Babes.
Manager Matt Busby spent the next decade re-building his club and his team and they emerged victorious with Bobby Charlton, who survived the plane crash, scoring twice, George Best once and Brian Kidd once, on his 19th birthday.
It could all have been very different though, if Eusebio, clean through on goal in the dying minutes, had not fired straight into the arms of United keeper, Alex Stepney.
Barcelona, May 26 1999: MANCHESTER UNITED 2 BAYERN MUNICH 1
United staged the greatest comeback in a European final as goals from Teddy Sheringham and Ole Gunnar Solskjaer in stoppage time after the 90 minutes were up, gave them victory over Bayern who had led with a sixth-minute goal from Mario Basler.
UEFA president Lennart Johansson has told the story many times of how, when he left the VIP box to prepare to present the cup, Bayern were winning and by the time he got down in the lift to pitch level, he had missed both goals and United had won. It would have been Busby's 90th birthday.
Moscow, May 21 2008: MANCHESTER UNITED 1 CHELSEA 1
(Manchester United won 6-5 on penalties)
Another United win, another night of unrelenting drama in Moscow's rain-lashed Luzhniki Stadium as the first all-English final and the first in Russia ended in a stalemate after 120 minutes with Ronaldo and Frank Lampard both scoring in the first half.
The match was finally settled by penalties. After Ronaldo failed with his kick, Chelsea skipper John Terry only had to score his to give Chelsea victory, but he slipped as he shot and the ball went wide. Edwin Van der Sar finally sealed the victory when he saved Nicolas Anelka's effort.
Rome, May 27, 2009 BARCELONA 2 MANCHESTER UNITED 0
See above. Barcelona are looking for a repeat, United looking for revenge.
(Editing by Clare Fallon; To comment on this story email email@example.com)