FACTBOX: Largest healthcare acquisitions

(Reuters) - Teva Pharmaceutical Industries Ltd (TEVA.O: Quote, Profile, Research)(TEVA.TA: Quote, Profile, Research) said on Friday it would buy rival generic drugmaker Barr Pharmaceuticals Inc BRL.N for $7.46 billion to expand its leadership in the U.S. market and fortify its presence in Europe.

The deal ranks as the third biggest healthcare deal, both worldwide and in the U.S., this year, according to data from Thomson Reuters.

It trails Novartis AG's (NOVN.VX: Quote, Profile, Research) pending $38 billion acquisition of Alcon Inc (ACL.N: Quote, Profile, Research), and Takeda Pharmaceutical Co Ltd's (4502.T: Quote, Profile, Research) $8.7 billion acquisition of Millennium Pharmaceuticals Inc.

In terms of all healthcare deals on record, the Barr-Teva deal ranks as the 36th-biggest worldwide healthcare deal of all time, and the 23rd-largest ever in the United States.

The following list ranks the 10 largest healthcare deals, according to Thomson Reuters.

TARGET BUYER VALUE*

1. Warner-Lambert Co Pfizer Inc $89.2 billion

2. SmithKline Beecham Plc Glaxo Wellcome Plc $76.0 billion

3. Aventis SA Sanofi-Synthelabo SA $60.2 billion