Wales striker Hal Robson-Kanu has withdrawn from the squad for their World Cup qualifier against Serbia on Sunday, the Football Association of Wales (FAW) said on its official Twitter account.
Robson-Kanu, who scored three goals in 29 Premier League appearances for West Bromwich Albion last season, is the second striker to withdraw from the squad after Liverpool's Ben Woodburn sustained a calf injury.
No reason was given for his withdrawal.
Swansea City and Wales under-20 forward Daniel James will replace Robson-Kanu in the squad as Wales try to cut down the four-point gap to leaders Serbia and Ireland in UEFA Group D.
Real Madrid forward Gareth Bale is suspended for the match in Belgrade.
(Reporting by Aditi Prakash in Bengaluru, editing by Nick Mulvenney)