July 20, 2020 / 3:33 PM / Updated 17 hours ago

FACTBOX- The race for a coronavirus vaccine

 (Adds Merck; updates Russia vaccine, Sinovac, Inovio, CanSino, Sinopharm)
    Aug 11 (Reuters) - More than 150 vaccines are being developed and tested around the world to stop the COVID-19 pandemic, with 28 in human clinical
trials, according to the World Health Organization. Russia has become the first country in the world to grant regulatory approval to a COVID-19
vaccine after less than two months of human testing, President Vladimir Putin said on Tuesday.
    The following list tracks the latest developments from major drugmakers and research institutes that have started human trials for their vaccine
candidates.
    For a separate FACTBOX on treatments under development, click here:
   
 Company                      State of play                                        Development phase                              Story date/link
 Not applicable               Russia granted regulatory approval to a coronavirus  In final-stage clinical trials                 Aug 11             
                              vaccine, dubbed Sputnik V, developed by Moscow's                                                    
                              Gamaleya Research Institute.                                                                        
 AstraZeneca Plc              Vaccine produces immune response in early-stage      Final stage study in 1,077 healthy adults      July 20             
                              trials; Late-stage trials currently underway.                                                       
 Sinopharm                    Developing two vaccines, one of which has shown      Begins late-stage trials in Bahrain; testing   Aug. 10             
                              promise in humans.                                   up to 15,000 volunteers in Abu Dhabi.          
 Pfizer Inc         and       Vaccine produced virus-neutralizing antibodies in    Began pivotal global study that aims to        July 27             
 BioNTech SE                  early-stage trials                                   enroll 30,000 volunteers                       
 Moderna Inc                  Says on track to deliver up to 1 billion doses a     30,000-subject final stage trial began on      July 27             
                              year, beginning 2021.                                July 27.                                       
 Sinovac Biotech Ltd          Released positive results from mid-stage trials of   Launched final-stage trial in Indonesia.       Aug 11             
                              its vaccine.                                                                                        
 CanSino Biologics            Early results showed the China-based company's       Late-stage trials to begin in Saudi Arabia.    Aug 9             
                              vaccine is safe.                                                                                    
 Inovio Pharma                Vaccine candidate, found to be safe, induced immune  Mid-stage trials planned.                      Aug 10             
                              responses in healthy volunteers in an early-stage                                                   
                              study.                                                                                              
 Chongqing Zhifei Biological  The Chinese company's unit Anhui Zhifei Longcom      Mid-stage trial.                               July 10             
 Products                     Biopharmaceutical has begun human trials.                                                           
 Bharat Biotech               Vaccine approved for human trials in India.          Early- to mid-stage trials to start in July    June 29             
 Johnson & Johnson            In talks with Japan, Bill and Melinda Gates          Early stage trials to start in July,           July 16             
                              Foundation, and the European Union for vaccine       late-stage study planned for September.        
                              allocations, Reuters reported.                                                                      
 Novavax Inc                  Vaccine produced high levels of antibodies,          Early-stage testing.                           July 7             
                              according to initial data from small study.                                                         
 GlaxoSmithKline Plc          Partnered with Sanofi SA           to develop a      Early stage trials to begin in September.      July 29             
                              vaccine.                                                                                            
 CureVac                      German biotech expects data in September or          Early-stage trial.                             Aug 10             
                              October; files for IPO in U.S.                                                                      
 Clover Biopharmaceuticals    The Chinese developer received $66 million in        Early-stage trials.                            July 8             
                              investment from an epidemic response group.                                                         
 Not applicable               Scientists at Imperial College London are running    Early-stage trials.                            June 15             
                              trials of a potential coronavirus vaccine.                                                          
 Genexine Inc                 South Korea's Genexine has begun human trials of     Early-stage trials.                            June 19             
                              its vaccine.                                                                                        
 Not applicable               Researchers at Institute of Medical Biology at       Mid-stage trials.                              June 21             
                              Chinese Academy of Medical Sciences are testing a                                                   
                              coronavirus vaccine.                                                                                
 Walvax Biotechnology Co      Trials sponsored by the China-based company, along   Early-stage studies.                           June 24             
                              with a Chinese military research institute, have                                                    
                              begun.                                                                                              
 Medicago                     Studying a plant-based vaccine.                      Early-stage trials.                            July 14             
 Cadila Healthcare Ltd        Plans to finish late-stage trials by early 2021.     Early-stage trials.                            July 17             
                                                                                                                                  
 Not applicable               University of Queensland began human trials in       Early-stage testing.                           July 14 (bit.ly/2Eo5iDg)
                              collaboration with Australian biotech company CSL                                                   
                                      .                                                                                           
 Arcturus Therapeutics        Dosed first group of participants in early-stage     Early-stage testing, with results expected in  Aug. 11            
          and Duke-NUS        clinical trials.                                     fourth quarter                                 
 Osaka University, AnGes,     A single-center trial in 30 healthy volunteers.      Early-stage testing.                           June 29 (bit.ly/3gaEiFB)
 Takara Bio                                                                                                                       
 Kentucky BioprocessingInc    Expects to begin trial of vaccine candidate in 180   Early-stage testing.                           July 28 (bit.ly/2BJDU1M)
                              adults on July 31.                                                                                  
 Vaxine Pty Ltd/Medytox       Expects to start mid-stage trials in next few        Early-stage testing.                           July 29             
                              weeks.                                                                                              
 Medigen Vaccine Biologics    Expects to begin early-stage study in 45 people on   Early-stage trial.                             July 27 (bit.ly/2XbnAOS)
 Corp/NIAID/Dynavax           Sept 1.                                                                                             
 Merck & Co Inc               Expects to begin human trials of its experimental    Early-stage trial planned.                     July 31             
                              vaccines later this year.                                                                           
 
 (Reporting by Vishwadha Chander and Manas Mishra in Bengaluru; Editing by Sriraj Kalluvila, Shailesh Kuber, Maju Samuel and Uttaresh.V)
  
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