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Cellectis SA (CLLS.OQ)

CLLS.OQ on NASDAQ Stock Exchange Global Market

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3 Aug 2020
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Summary

Name Age Since Current Position

Andre Choulika

55 2000 Chairman of the Board, Chief Executive Officer, Co-Founder, Member of the Executive Board

David Sourdive

53 2019 Co-Founder, Executive Vice President, Strategic Initiatives, Member of the Executive Committee, Director

Eric Dutang

46 2016 Chief Financial Officer, Member of the Executive Committee

William Montelth

62 2019 Executive Vice President of Technical Operations, Member of the Executive Committee

Jon Voss

60 2019 Executive Vice President - Global Quality, Member of the Executive Committee

Leopold Bertea

2020 Senior Vice President - Technical Operations - Europe

Steve Doares

2020 Senior Vice President of US Manufacturing

Philippe Duchateau

57 2012 Chief Scientific Officer, Member of the Executive Committee

Stephan Reynier

51 Chief Regulatory and Compliance Officer, Member of the Executive Committee

Arthur Stril

31 2018 Vice President - Corporate Development, Member of the Executive Committee

Marie-Bleuenn Terrier

38 2013 General Counsel, Member of the Executive Committee

Laurent Arthaud

57 2011 Non-Executive Independent Director

Pierre Bastid

65 2011 Non-Executive Independent Director

Rainer Boehm

60 2017 Non-Executive Independent Director

Alain Godard

74 2007 Non-Executive Independent Director

Herve Hoppenot

60 2017 Non-Executive Independent Director

Annick Schwebig

69 2011 Non-Executive Independent Director

Simon Harnest

2019 Investor Relations, USA

Biographies

Name Description

Andre Choulika

Dr. Andre Choulika Ph.D. serves as Chairman of the Board, Chief Executive Officer, Co-Founder, Member of the Executive Board of the Company. He is one of the founders of Cellectis and served as Chief Executive Officer since the company’s inception in 1999. He is Chairman of the Board of Directors since 2011 and President of the board of directors of Calyxt, Inc. since August 2010. He is CEO and Chairman of Cellectis, Inc. since December 2014 and Cellectis Biologics, Inc. since January 2019. From 1997 to 1999, Dr. Choulika worked as a post-doctoral fellow in the Division of Molecular Medicine at Boston Children’s Hospital, where he was one of the inventors of nuclease-based genome editing technologies and a pioneer in the analysis and use of meganucleases to modify complex genomes. After receiving his Ph.D. in molecular virology from the University of Paris VI (Pierre et Marie Curie), he completed a research fellowship in the Harvard Medical School Department of Genetics. His management training is from HEC (Challenge +). Since June 2019, Dr. Choulika served at the board of directors of Institut Pasteur.

David Sourdive

Dr. David J.D. Sourdive Ph.D. serves as Co-Founder, Executive Vice President, Strategic Initiatives, Member of the Executive Committee, Director of the Company. He previously served as Director, Executive Vice President Technical Operations, Member of Executive Committee and Deputy Chief Executive Officer at the company as of 2016. Previously he served as Company's Executive Vice President-Corporate Development and Director. From 2014, Dr. Sourdive also served on the Board of Directors of Mediterranean Institute for Life Sciences. He previously served on the Board of Directors of Medicen Paris Region and Seine Saint Denis Avenir. From 1998 to 2000, he directed the biotechnologies laboratory of the Centre d’Etudes du Bouchet for the French Ministry of Defense. Dr. Sourdive graduated from the Ecole Polytechnique and received his Ph.D. in molecular virology at the Institut Pasteur. He also has management training from the HEC (Challenge +). He is currently on the Board of Directors within MEDILS, Eukarys SAS and Omics SAS.

Eric Dutang

Mr. Eric Dutang serves as Chief Financial Officer, Member of the Executive Committee of the Company. He joined us as Deputy Chief Financial Officer in May 2015 and was appointed Chief Financial Officer in 2016. Eric began his career as financial auditor with KPMG, first in Paris for five years and then in New York for two years. He worked for listed companies in France and the United States such as Vivendi, Veolia Environnement or Cablevision. He then became a member of the transactions and advisory teams in Paris for seven years where he carried out acquisitions / disposals for listed companies and private equity funds. After serving at KPMG, he worked on international business developments for French public listed groups, including Air Liquide and Thales. Eric holds a Master of Finance and Executive MBA from HEC Paris (France)/Babson Massachusetts (USA).

William Montelth

Mr. William Montelth serves as Executive Vice President of Technical Operations, Member of the Executive Committee of the Company. He joined Cellectis in November 2018 as Senior Vice President US Manufacturing responsible for the selection, construction and buildout of Cellectis’ manufacturing facility located at Raleigh, North Carolina. Bill Monteith was named Executive Vice President of Technical Operations in July 2019. Before joining Cellectis, Mr. Monteith was the Chief Operating Officer for Hitachi Chemical Advanced Therapeutic Solutions (formerly PCT). While at Hitachi, Mr. Monteith was part of the executive team overseeing the merger with Hitachi and went on to build a cell and gene therapy facility in Yokohama Japan in addition to being responsible for the US based facilities in Allendale New Jersey and Mountain View California. Prior to that, Mr. Monteith was the VP and General Manager, and then Executive VP, Technical Operations, for Dendreon which was the first autologous cellular therapy to get approval in the United States. Mr. Monteith has also held leadership roles at Sandoz, Shire, and Wyeth pharmaceuticals, ranging from technical operations to quality assurance. Mr. Monteith received his Bachelor of Science in pre-medical studies with a major in Chemistry from Saint Lawrence University in Canton, NY.

Jon Voss

Mr. Jon Voss serves as Executive Vice President - Global Quality, Member of the Executive Committee of the Company. Mr. Voss joined Cellectis in July 2019 as Executive Vice President of Global Quality. Mr. Voss has over 30 years of US and international Quality expertise in gene therapy, small molecule, biologic and medical device products working as VP of Quality for such companies as Generation Bio, Sarepta Therapeutics and Genzyme. Having worked in early stage pre-clinical, clinical and commercial organizations, Mr. Voss has unique experience in moving companies from the development to commercial stage. As EVP of Global Quality, Mr. Voss is building the Cellectis global quality organization to support the existing Cellectis UCART clinical programs as well as ensuring that Cellectis is prepared for commercial licensure and the associated operations. Mr. Voss earned his Bachelor of Science degree from the University of California at Davis and received his Master of Science in Biomedical Engineering from Boston University.

Leopold Bertea

Dr. Leopold Bertea serves as Senior Vice President - Technical Operations - Europe of the Company. Leopold Bertea joins Cellectis as a recognized biopharmaceutical leader at several pharmaceutical companies. He is also known for his expertise in biopharmaceutical production and development. First with Novartis, where he was in charge of commercial monoclonal antibody production, and later with Sanofi where he built up and led the first integrated Biologics CMC Platform, covering the company's biologics pipeline. Dr. Bertea then covered roles as Vice President Bio-business & Governance for Sanofi's Global Biotherapeutics, managing the collaboration projects with partners. He was also a member of the Sanofi global R&D Leading team and a senior Biologics Expert. Leopold Bertea holds a Ph.D. in Chemical Engineering from ETH Zürich.

Steve Doares

Mr. Steve Doares serves as Senior Vice President of US Manufacturing of the Company. Steve Doares joins Cellectis from Biogen where he was VP, Global Manufacturing Sciences, responsible for technology transfer into GMP manufacturing of processes from clinical through commercialization stages for Biogen's therapeutic product portfolio, both internally and externally. In his previous role, he provided scientific expertise for process troubleshooting and lifecycle improvements; process monitoring, advanced modeling, and PAT implementation; and technical and vendor management expertise for raw materials and SUS/disposables. Steve was also overseeing both drug substance/API and drug product processes, for biologics and pharmaceuticals, and was with Biogen since 2010. Before that, he spent 15 years at Wyeth/Pfizer in glycoconjugate vaccine process development and technology transfer, clinical trials material drug substance production, and quality assurance supporting a vaccine drug substance plant. Dr. Doares holds a Ph.D. in Biochemistry from the University of Georgia.

Philippe Duchateau

Dr. Philippe Duchateau Ph.D. serves as Chief Scientific Officer, Member of the Executive Committee of the Company. He joined Cellectis in 2001 to pioneer the field of genome engineering and has served as Chief Scientific Officer since 2012. After receiving his PhD in 1993 in biochemistry and molecular biology at the Institut Pasteur (Lille, France), he completed a research fellowship from 1993 to 2001 at the University of California, San Francisco (United States) within the Cardiovascular Research Institute. He is co-inventor of numerous patents in the field of nucleases and genome engineering and co-authors on more than 50 scientific publications and co-editor of one book entitled “Site-directed Insertion of Transgenes.” As head of Cellectis’s Research department since 2004, he helped to the development of the Cellectis Technologies.

Stephan Reynier

Mr. Stephan Reynier serves as Chief Regulatory and Compliance Officer, Member of the Executive Committee of the Company. He joined Cellectis in April 2011. He serves as Chief Regulatory and Compliance Officer after holding the position of Head of Programs at Ectycell, a former subsidiary of Cellectis, from April 2011 to 2014 with the mission of managing and coordinating internal and external collaborative programs. As Chief Regulatory and Compliance Officer, Mr. Reynier is in charge of ensuring a speedy and successful development of the UCART product family by establishing close interactions with regulatory agencies such as EMA and FDA, while securing compliance to applicable regulations, regulatory guidelines and quality assurance standards. Mr. Reynier has extensive experience, from his previous positions as Senior Director at Voisin Consulting Life Sciences and European Associate Director Medical Affairs at Gilead Sciences, in the design and implementation of regulatory strategies for the development of drugs and biologics, with a strong focus on cell and gene therapy. Mr Reynier graduated as Agro-Engineer in France and received a Master of Science in Chemical Engineering from the University of Toronto, Canada.

Arthur Stril

Mr. Arthur Stril serves as Vice President - Corporate Development, Member of the Executive Committee of the Company. He joined Cellectis in July 2018 as Vice President, Corporate Development and is responsible for program management, strategy and business development. Arthur began his career at the European Commission’s Directorate-General for Competition, controlling global pharmaceutical mergers. He later became Head of the Hospital Financing Unit at the French Ministry of Health. Mr. Stril graduated from the École Normale Supérieure, Paris & Cambridge University, and holds a diploma in Immunotherapy from the Université Paris-Descartes. Mr. Stril is also a member of the French Corps des Mines.

Marie-Bleuenn Terrier

Ms. Marie-Bleuenn Terrier serves as General Counsel, Member of the Executive Committee of the Company. She joined Cellectis as Legal Counsel in 2008, and was appointed General Counsel in 2013. Prior to joining Cellectis, she worked as Legal Counsel for Pfizer from 2004 to 2006, and for Boehringer-Ingelheim from 2006 to 2008. Marie-Bleuenn Terrier has also served as Secretary of our board of directors since 2015. She holds a Master’s degree in Law from the Panthéon La Sorbonne University in Paris.

Laurent Arthaud

Mr. Laurent Arthaud serves as Non-Executive Independent Director of the Company. He has served as a member of our board of directors since October 28, 2011. Mr. Arthaud has been the Managing Director of Life Sciences and Ecotechnologies for Bpifrance Investissement (formerly CDC Enterprises, a subsidiary of Caisse des Dépôts) since 2012. He currently serves on the boards of directors of Kurma Life Sciences Partners, Adocia, Sparingvision, Aledia and Ribogenics, Inc. and Enyo Pharma. He served on the board of directors of TxCell from 2012 to 2018, on the board of directors of Emertee Gestion from 2006 to 2016, and on the board of directors of Scynexis, Inc. from 200 to 2015. From 2006 to 2012, Mr. Arthaud held the position of Deputy CEO at CDC Entreprises. Since 2009 Mr. Arthaud has also directed InnoBio, an investment fund managed by Bpifrance Investissement as part of the FSI France Investissement program. From 1999 to 2004 he served as Vice President of Aventis Capital, an investment subsidiary of the pharmaceuticals group Aventis, and as President of Pharmavent Partners from 2004 to 2006. Mr. Arthaud is a graduate of the École Polytechnique and the École Nationale de Statistique et d’Administration Économique.

Pierre Bastid

Mr. Pierre Bastid serves as Non-Executive Independent Director of the Company. He has served as a member of Cellectis’ board of directors since 2011. Mr. Bastid has 25 years experience in turning around, developing and running technology businesses in Asia, Europe and the United States. In addition to Cellectis, Mr. Bastid is currently serving on the board of directors of Pharnext (a biotechnology company), and DCTV Center New-York, and of a series of his owned investment and private equity companies. Mr. Bastid also advises a number of investment and private equity firms. Mr. Bastid is a trustee of the Juilliard School of Music and other non-profit organizations based in the United States.

Rainer Boehm

Mr. Rainer J. Boehm M.D. serves as Non-Executive Independent Director of the Company. He has served as a member of Cellectis’ board of directors since 2017. In addition, Mr. Boehm is currently serving on the board of directors of Humanigen, Inc. and Nordic Nanovector ASA since 2018. Since 2019, he served on the board of directors of BioCopy AG. Mr. Boehm spent 29 years at Novartis, working locally, regionally and globally in various Senior Management roles, after building his career in Marketing & Sales and Medical Affairs. He led all emerging markets regions as well as the United States and Canada, either for Oncology or the Pharmaceuticals division. His most recent assignments were Chief Commercial and Medical Affairs Officer globally for Novartis Pharma, as well as ad interim CEO and Division Head Pharma. Rainer launched and oversaw the commercialization of many brands during his career, amongst them Femara, Zometa and Glivec, as well as Cosentyx and Entresto. Rainer has a medical degree from the University of Ulm in Germany, and a Master of Business Administration from Schiller University in France.

Alain Godard

Mr. Alain Godard serves as Non-Executive Independent Director of the Company. He has served as a member of Cellectis’ board of directors since 2007. In addition, Mr. Godard is currently serving on the board of directors of Calyxt, Inc. He is a graduate of the Ecole Nationale Supérieure Agronomique de Toulouse and began his agronomy career in 1967 in Africa as a researcher at the Institut de Recherche pour les Huiles et Oléagineux. He joined the French chemical group Rhône-Poulenc in 1975 where he held various management positions in France and abroad before becoming CEO of the agrochemical subsidiary in 1991. In 1999 he was directly involved in the merger of Rhône-Poulenc and Hoechst to create Aventis and was appointed CEO of the Aventis CropScience subsidiary with a significant involvement in seeds and agricultural biotechnology. He left Aventis in 2002 to create a consulting company, SARL Godard & Co., specialized in agriculture and biotechnology, where he has served as Chief Executive Officer since 2009. Until 2016, Mr. Godard also served on the board of directors of Fermentalg S.A.

Herve Hoppenot

Mr. Herve Hoppenot serves as Non-Executive Independent Director of the Company. He has served as a member of Cellectis’ board of directors since 2017. He serves as President and Chief Executive Officer of Incyte Corporation since 2014, and was appointed Chairman of the Board of Directors in 2015. Incyte is one of the fastest growing biopharmaceutical companies in the U.S. Prior to joining Incyte, Mr. Hoppenot was the President of Novartis Oncology, which included $11 billion in global sales, the largest oncology pipeline in the industry and 8000 employees in 50 countries. Prior to joining Novartis in 2003, Mr. Hoppenot started his career in 1983 with Rhone Poulenc, later known as Aventis, where he served in several senior roles of increasing responsibility, including Vice President of Oncology and Head of the US Oncology business unit. He and his family are dual citizens of France and the United States, having moved to the U.S. in 1991.

Annick Schwebig

Dr. Annick Schwebig M.D. serves as Non-Executive Independent Director of the Company. She has served as a member of our board of directors since October 28, 2011. In 2000, she founded the French subsidiary of Actelion, of which she is a Senior Advisor. She formerly served as the General Manager of Actelion from 2000 to 2015. Actelion is a biopharmaceutical company specializing in innovative treatments to serve unmet medical needs. She is also a director of Inventiva Pharma, a biopharmaceutical company, and B Cell Design, a biotechnologies company. A graduate of the University of Paris medical school, Dr. Schwebig worked as a senior manager at the biopharmaceuticals company Bristol-Myers Squibb for 17 years from 1983 to 2000.

Simon Harnest